ISSN 1662-4009 (online)

ey0017.15-7 | (1) | ESPEYB17

15.7. Childhood obesity intervention studies: A narrative review and guide for investigators, authors, editors, reviewers, journalists, and readers to guard against exaggerated effectiveness claims

AW Brown , DG Altman , T Baranowski , JM Bland , JA Dawson , NV Dhurandhar , S Dowla , KR Fontaine , A Gelman , SB Heymsfield , W Jayawardene , SW Keith , TK Kyle , E Loken , JM Oakes , J Stevens , DM Thomas , DB Allison

To read the full abstract: Obes Rev. 2019 Nov;20(11):1523–1541. doi: 10.1111/obr.12923.This is a thoughtful position statement by a number of leading obesity researchers and statisticians. They draw attention to 10 errors that are common in the scientific literature: 1. Using self-reported outcomes and ‘teaching to the test’ (achieving better scores simply by repeat testing); 2. L...

ey0018.11-10 | Mechanism of the year | ESPEYB18

11.10. Intercellular mitochondria transfer to macrophages regulates white adipose tissue homeostasis and is impaired in obesity

JR Brestoff , CB Wilen , JR Moley , Y Li , W Zou , NP Malvin , MN Rowen , BT Saunders , H Ma , MR Mack , BL Hykes , DR Balce , A Orvedahl , JW Williams , N Rohatgi , X Wang , MR McAllaster , SA Handley , BS Kim , JG Doench , BH Zinselmeyer , MS Diamond , HW Virgin , AE Gelman , SL Teitelbaum

Cell Metab 2021;33(2): 270–282.e8. doi: https://doi.org/10.1016/j.cmet.2020.11.008Brestoff et al. show, for the first time, that mitochondria are transferred from adipocytes to macrophages and that this event has an impact on systemic metabolic homeostasis.Within the last years, it has been demonstrated that cells are able to communicate with each other by the exchange of organell...